PD-1/PD-L1-IN-21

Names

[ CAS No. ]:
2158336-16-2

[ Name ]:
PD-1/PD-L1-IN-21

Biological Activity

[Description]:

PD-1/PD-L1-IN-21 (Example 22) is a small-molecule inhibitor of the PD-1/PD-L1 protein-protein interaction. PD-1/PD-L1-IN-21 blocks PD-1/PD-L1 with the IC50 of 4.99 μM. PD-1/PD-L1-IN-21 can be used for the research of cancers, infectious diseases and autoimmune diseases[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Immunology/Inflammation >> PD-1/PD-L1

[References]

[1]. Nicotinyl alcohol ether derivative, preparation method therefor, and pharmaceutical composition and uses thereof. WO2017202274A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C32H32BrClN2O4

[ Molecular Weight ]:
623.96

Related Compounds