<Suppliers Price>

BPK-29

Names

[ CAS No. ]:
2143467-62-1

[ Name ]:
BPK-29

Biological Activity

[Description]:

BPK-29 is a covalent small molecule that disrupts NR0B1 complexes and impairs the anchorage-independent growth of KEAP1-mutant cancer cells[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

BPK-29 substantially engages NR0B1 with good overall proteomic selectivity in KEAP1-mutant Non-Small Cell Lung Cancers[1].

[References]

[1]. Woodruff TM,et al. The complement factor C5a contributes to pathology in a rat model of amyotrophic lateral sclerosis. J Immunol. 2008 Dec 15;181(12):8727-34.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H32ClN3O3

[ Molecular Weight ]:
470.00

Related Compounds