AZD-5991 Racemate

Names

[ Name ]:
AZD-5991 Racemate

Biological Activity

[Description]:

AZD-5991 Racemate is the racemate of AZD-5991. AZD-5991 Racemate is a Mcl-1 inhibitor with an IC50 of <3 nM in FRET assay.

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Bcl-2 Family

Research Areas >> Cancer

[Target]

Mcl-1:3 nM (IC50)

[References]

[1]. Tron AE, et al. Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia. Nat Commun. 2018 Dec 17;9(1):5341.

[Related Small Molecules]

Venetoclax (ABT-199) | ABT-263 | S63845 | ABT-737 | Obatoclax Mesylate | A-1210477 | A-1155463 | WEHI-539 hydrochloride | A-1331852 | Bax inhibitor peptide V5 | FX 1 | Gambogic Acid | TW-37 | UMI-77 | Acetate gossypol

Chemical & Physical Properties

[ Density]:
1.42±0.1 g/cm3(Predicted)

[ Boiling Point ]:
949.6±65.0 °C(Predicted)

[ Molecular Formula ]:
C₃₅H₃₄ClN₅O₃S₂

[ Molecular Weight ]:
672.26

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xn

Related Compounds

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