3,4-Didehydroglabridin

Names

[ Name ]:
3,4-Didehydroglabridin

Biological Activity

[Description]:

3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

3,4-Didehydroglabridin (10 μM) 可以逆转 CCl4 诱导的 HepG2 毒性，将细胞活力从 52.5% 提高到 >80%[2]。

[References]

[1]. Kinoshita T, et, al. The isolation and structure elucidation of minor isoflavonoids from licorice of Glycyrrhiza glabra origin. Chem Pharm Bull (Tokyo). 2005 Jul;53(7):847-9.

[2]. Kuang Y, et, al. Screening of hepatoprotective compounds from licorice against carbon tetrachloride and acetaminophen induced HepG2 cells injury. Phytomedicine. 2017 Oct 15;34:59-66.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₁₈O₄

[ Molecular Weight ]:
322.35

Related Compounds

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