Thalidomide-4-NH-PEG1-COOH TFA

Names

[ CAS No. ]:
2140807-20-9

[ Name ]:
Thalidomide-4-NH-PEG1-COOH TFA

Biological Activity

[Description]:

Thalidomide-4-NH-PEG1-COOH TFA is an E3 Ligase Ligand-Linker Conjugate consisting of Thalidomide (HY-14658) and NH-PEG3-NH-Boc. Thalidomide-4-NH-PEG1-COOH TFA acts as a ligand for Cereblon to recruit CRBN protein. Thalidomide-4-NH-PEG1-COOH TFA is a key intermediate in the synthesis of CRBN-based PROTAC molecules.

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

Chemical & Physical Properties

[ Molecular Formula ]:
C20H20F3N3O9

[ Molecular Weight ]:
503.38

Related Compounds

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