Pomalidomide-PEG2-COOH

Names

[ Name ]:
Pomalidomide-PEG2-COOH

Biological Activity

[Description]:

Pomalidomide-PEG2-COOH is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> E3 Ligase Ligand-Linker Conjugate

[References]

[1]. Fangqing Zhang, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₃N₃O₈

[ Molecular Weight ]:
433.41

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds

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