Odesivimab

Names

[ Name ]:
Odesivimab

Biological Activity

[Description]:

Odesivimab is a humanized monoclonal antibody, targeting Ebola virus glycoprotein with a KD value of 7.74 nM for recombinant histidine-tagged Makona strain Ebola virus glycoprotein ectodomain protein. Odesivimab can be used in research of Ebola virus infection[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Influenza Virus

Research Areas >> Infection

[In Vitro]

Odesivimab (REGN-3471) 在体外中和假病毒颗粒。Odesivimab 与 Atoltivimab 和 Maftivimab 的 IC50 值为 0.39 nM[1]。

[In Vivo]

Odesivimab 与 Atoltivimab 和Maftivimab (REGN-3471; 50 mg/kg) 对埃博拉病毒感染的恒河猴模型具有保护作用[1]。

[References]

[1]. Markham A. REGN-EB3: First Approval. Drugs. 2021 Jan;81(1):175-178.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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