KHK-IN-2

Names

[ CAS No. ]:
2135304-43-5

[ Name ]:
KHK-IN-2

Biological Activity

[Description]:

KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Hexokinase

Research Areas >> Metabolic Disease

[Target]

IC50: 0.45 μM (KHK)[1]

[References]

[1]. Huard K, et al. Discovery of Fragment-Derived Small Molecules for in Vivo Inhibition of Ketohexokinase (KHK). J Med Chem. 2017 Sep 28;60(18):7835-7849.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₉F₃N₄O₃

[ Molecular Weight ]:
372.34

Related Compounds

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