6H-Purine-6-thione,2-amino-9-(2-deoxy-a-D-erythro-pentofuranosyl)-1,9-dihydro-
Names
[ CAS No. ]:
2133-81-5
[ Name ]:
6H-Purine-6-thione,2-amino-9-(2-deoxy-a-D-erythro-pentofuranosyl)-1,9-dihydro-
Chemical & Physical Properties
[ Density]:
2.02g/cm3
[ Boiling Point ]:
709.1ºC at 760 mmHg
[ Molecular Formula ]:
C10H13N5O3S
[ Molecular Weight ]:
283.30700
[ Flash Point ]:
382.6ºC
[ Exact Mass ]:
283.07400
[ PSA ]:
154.30000
[ LogP ]:
0.29300
[ Vapour Pressure ]:
4.22E-21mmHg at 25°C
[ Index of Refraction ]:
1.93
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UP0745000
- CHEMICAL NAME :
- 9H-Purine-6(1H)-thione, 2-amino-9-(2-deoxy-alpha-D-erythro-pentofuranosyl)-
- CAS REGISTRY NUMBER :
- 2133-81-5
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C10-H13-N5-O3-S
- MOLECULAR WEIGHT :
- 283.34
- WISWESSER LINE NOTATION :
- T56 BN DN FYM INJ FUS HZ B- ET5OTJ B1Q CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1 gm/kg/5D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 1500 mg/kg/33D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - leukopenia Blood - thrombocytopenia
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Primate - monkey
- DOSE/DURATION :
- 3 gm/kg/5D-I
- TOXIC EFFECTS :
- Gastrointestinal - nausea or vomiting Blood - agranulocytosis Skin and Appendages - dermatitis, other (after systemic exposure)
MUTATION DATA
- TYPE OF TEST :
- Host-mediated assay
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 100 umol/kg
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,1103,1975
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.