YW1159

Names

[ Name ]:
YW1159

[Synonym ]:
1-(2-Fluorophenyl)-5-methyl-N-(2-quinolinyl)-1H-1,2,3-triazole-4-carboxamide
1H-1,2,3-Triazole-4-carboxamide, 1-(2-fluorophenyl)-5-methyl-N-2-quinolinyl-

Biological Activity

[Description]:

YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.

[In Vitro]

YW1159 is an inhibitor of Wnt signaling with an IC50 value of 1.2 nM in a reporter assay.It is not cytotoxic to HEK293 cells following incubations of up to 24 hours but cell viability is decreased in a concentration-dependent manner after 72 hours.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₉H₁₄FN₅O

[ Molecular Weight ]:
347.346

[ Exact Mass ]:
347.118225

[ LogP ]:
2.72

[ Index of Refraction ]:
1.688

Related Compounds

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