3,3',4,4'-TETRACHLOROAZOXYBENZENE
Names
[ CAS No. ]:
21232-47-3
[ Name ]:
3,3',4,4'-TETRACHLOROAZOXYBENZENE
[Synonym ]:
Diazene,bis(3,4-dichlorophenyl)-,1-oxide
3,3',4,4'-tetrachloroazoxybenzole
TCAOB
bis-(3,4-dichloro-phenyl)-diazene-N-oxide
Azoxybenzene,3,3',4,4'-tetrachloro
3,3',4,4'-Tetrachlor-azoxybenzol
3,3',4,4'-TETRACHLOROAZOXYBENZENE
Bis-(3,4-dichlor-phenyl)-diazen-N-oxid
Bis(3,4-dichlorophenyl)diazene 1-oxide
3,4,3',4'-Tetrachloroazoxybenzene
3,4,3',4'-Tetrachlor-azoxybenzol
Chemical & Physical Properties
[ Density]:
1.53g/cm3
[ Boiling Point ]:
472.7ºC at 760 mmHg
[ Molecular Formula ]:
C12H6Cl4N2O
[ Molecular Weight ]:
336.00100
[ Flash Point ]:
239.7ºC
[ Exact Mass ]:
333.92300
[ PSA ]:
41.11000
[ LogP ]:
6.74910
[ Vapour Pressure ]:
1.19E-08mmHg at 25°C
[ Index of Refraction ]:
1.641
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CO4150000
- CHEMICAL NAME :
- Azoxybenzene, 3,3',4,4'-tetrachloro-
- CAS REGISTRY NUMBER :
- 21232-47-3
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 11
- MOLECULAR FORMULA :
- C12-H6-Cl4-N2-O
- MOLECULAR WEIGHT :
- 336.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 mg/kg/17W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in erythrocyte (RBC) count Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 650 mg/kg/13W-I
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 350 mg/kg/48D-I
- TOXIC EFFECTS :
- Liver - other changes Endocrine - changes in thymus weight Related to Chronic Data - changes in testicular weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 200 mg/kg/28D-I
- TOXIC EFFECTS :
- Liver - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 75600 ug/kg
- SEX/DURATION :
- female 14 day(s) pre-mating - 28 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - blood and lymphatic systems (including spleen and marrow) Reproductive - Effects on Newborn - live birth index (measured after birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 7560 ug/kg
- SEX/DURATION :
- female 14 day(s) pre-mating - 28 day(s) post-birth
- TOXIC EFFECTS :
- Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 16 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Effects on Embryo or Fetus - fetal death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 6 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) Reproductive - Specific Developmental Abnormalities - urogenital system
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 134 mg/kg/4W (Continuous)
- REFERENCE :
- AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,677,1985