TH1834

Names

[ Name ]:
TH1834

Biological Activity

[Description]:

TH1834 (TH-1834, TH 1834) is a novel potent specific histone acetyltransferase Tip60 inhibitor; induces apoptosis in breast cancer cell lines with more cytotoxicity than staurosporine; increases the γH2AX foci in the cancer cell lines PC-3 and DU-145 combined with IR; induces apoptosis and increases unrepaired DNA damage in breast cancer cells.

[References]

References 1. Gao C, et al. Sci Rep. 2014 Jun 20;4:5372. View Related Products by Target Histone Acetyltransferase (HAT)

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₄₀N₆O₃

[ Molecular Weight ]:
568.722

Related Compounds

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