4-(4-nitro-phenyl)-thiazol-2-ylamine
Names
[ CAS No. ]:
2104-09-8
[ Name ]:
4-(4-nitro-phenyl)-thiazol-2-ylamine
[Synonym ]:
2-Thiazolamine,4-(4-nitrophenyl)
4-(4-NITRO-PHENYL)-THIAZOL-2-YLAMINE
2-Amino-4-(4-nitrophenyl)thiazole
4-(4-NITROPHENYL)THIAZOL-2-AMINE
2-Amino-4-(p-nitrophenyl)thiazole
4-(4-NITROPHENYL)-1,3-THIAZOLE-2-YLAMINE
4-(4-Nitrophenyl)-2-thiazolamine
2-AMINO-4-(4-NITROPHENYL)-1,3-THIAZOLE
THIAZOLE,2-AMINO-4-(p-NITROPHENYL)
2-amino-4-(4'-nitrophenyl)-1,3-thiazole
2-THIAZOLAMINE,4-(4-NITROPHENYL)-
4-(4-NITROPHENYL)-2-THIAZOLYLAMINE
4-(4-NITROPHENYL)THIAZOL-2-YLAMINE
MFCD00170222
Chemical & Physical Properties
[ Density]:
1.459g/cm3
[ Boiling Point ]:
448.4ºC at 760 mmHg
[ Melting Point ]:
283-287ºC
[ Molecular Formula ]:
C9H7N3O2S
[ Molecular Weight ]:
221.23600
[ Flash Point ]:
225ºC
[ Exact Mass ]:
221.02600
[ PSA ]:
112.97000
[ LogP ]:
3.40490
[ Vapour Pressure ]:
3.11E-08mmHg at 25°C
[ Index of Refraction ]:
1.692
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XJ2860000
- CHEMICAL NAME :
- Thiazole, 2-amino-4-(p-nitrophenyl)-
- CAS REGISTRY NUMBER :
- 2104-09-8
- BEILSTEIN REFERENCE NO. :
- 0200321
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H7-N3-O2-S
- MOLECULAR WEIGHT :
- 221.25
- WISWESSER LINE NOTATION :
- T5N CSJ BZ ER DNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2150 mg/kg/13W-C
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors Skin and Appendages - tumors
- REFERENCE :
- JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 54,841,1975
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9600 mg/kg/46W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Blood - leukemia
- REFERENCE :
- CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,1593,1973
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
XJ2860000
[ HS Code ]:
2934100090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Biomed. Mass Spectrom. 9(9) , 376-80, (1982)
Electron impact fragmentation of 2-methyl-4-(4-nitrophenyl)-thiazole and 2-amino-4-(4-nitrophenyl)-thiazoles were studied. Prominent fragment ions result from: (1) elimination of an NO2 radical and of...