UHMCP1

Names

[ Name ]:
UHMCP1

Biological Activity

[Description]:

UHMCP1 is a small molecule that prevents the SF3b155/U2AF65 interaction, binds to the hydrophobic pocket of the U2AF65 UHM domain (Kd=1-20 uM), impacts splicing and cell viability.

[References]

1. Asaki Kobayashi, et al. FEBS J. 2022 Feb;289(3):682-698.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₇N₃

[ Molecular Weight ]:
297.446

Related Compounds

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