VH 032, propargyl

Names

[ CAS No. ]:
2098799-78-9

[ Name ]:
VH 032, propargyl

Biological Activity

[Description]:

(S,R,S)-AHPC-propargyl (VH032-propargyl) is a VHL ligand which is used in “click reaction” for PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

[References]

[1]. Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing Protein Degradation. J Med Chem. 2018 Jan 25;61(2):453-461.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₃₄N₄O₅S

[ Molecular Weight ]:
526.65

Related Compounds

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