LOXO-195 RS-isomer

Names

[ CAS No. ]:
2097002-59-8

[ Name ]:
LOXO-195 RS-isomer

Biological Activity

[Description]:

The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.

[References]

References 1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972. View Related Products by Target Trk Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₁FN₆O

[ Molecular Weight ]:
380.427

Related Compounds

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