LOXO-195 RS-isomer
Names
[ CAS No. ]:
2097002-59-8
[ Name ]:
LOXO-195 RS-isomer
Biological Activity
[Description]:
The RS-isomer of LOXO-195, a potent, selective, next-generation Trk tyrosine kinase inhibitor with IC50 of 0.6 nM and <2.5 nM for WT TrkA and WT TrKC, respectively.
[References]
References 1. Drilon A, et al. Cancer Discov. 2017 Sep;7(9):963-972. View Related Products by Target Trk Receptor
Chemical & Physical Properties
[ Molecular Formula ]:
C20H21FN6O
[ Molecular Weight ]:
380.427