Tilsotolimod sodium

Names

[ CAS No. ]:
2089768-67-0

[ Name ]:
Tilsotolimod sodium

Biological Activity

[Description]:

Tilsotolimod (sodium) is a synthetic Toll-like receptor 9 (TLR9) agonist that has demonstrated antitumor activity in preclinical models.

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Toll-like Receptor (TLR)

Research Areas >> Cancer

[References]

[1]. Karime C, Wang J, Woodhead G, et al. Tilsotolimod: an investigational synthetic toll-like receptor 9 (TLR9) agonist for the treatment of refractory solid tumors and melanoma. Expert Opin Investig Drugs. 2022;31(1):1-13.

[2]. Haymaker C, Johnson DH, Murthy R, et al. Tilsotolimod with Ipilimumab Drives Tumor Responses in Anti-PD-1 Refractory Melanoma. Cancer Discov. 2021;11(8):1996-2013.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂₃H₂₆₂N₇₄Na₂₂O₁₁₅P₂₂S₂₂

[ Molecular Weight ]:
7711.51

Related Compounds

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