1,2,8-Trihydroxy-6-methoxyxanthone

Names

[ CAS No. ]:
20882-75-1

[ Name ]:
1,2,8-Trihydroxy-6-methoxyxanthone

[Synonym ]:
9H-Xanthen-9-one, 1,2,8-trihydroxy-6-methoxy-
1,7,8-Trihydroxy-3-methoxyxanthone
1,2,8-Trihydroxy-6-methoxy-9H-xanthen-9-one
6-Methoxy-1,2,8-trihydroxyxanthen-9-one
Swertianin
Xanthen-9-one,6-methoxy-1,2,8-trihydroxy
1,2,8-Trihydroxy-6-methoxyxanthone
1,2,8-trihydroxy-6-methoxy-xanthen-9-one
gentiakochianin
1,2,8-trihydroxy-6-methoxyxanthen-9-one

Biological Activity

[Description]:

Swertianine is a hydroxyexanthone that can be isolated from Swertia decussata. Swertianine has antioxidant activity by inhibiting lipid peroxidation, scavenging DPPH and superoxide free radicals. Swertianine also inhibits γ-ray induced DNA damage of pBR322 with protective effect[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Patro BS, et al. Antioxidant activities of Swertia decussata xanthones. Nat Prod Res. 2005 Jun;19(4):347-54.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
576.9±50.0 °C at 760 mmHg

[ Melting Point ]:
243℃

[ Molecular Formula ]:
C₁₄H₁₀O₆

[ Molecular Weight ]:
274.23

[ Flash Point ]:
226.7±23.6 °C

[ Exact Mass ]:
274.047729

[ PSA ]:
100.13000

[ LogP ]:
1.35

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.714

[ Storage condition ]:
2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: ZD6116600

CHEMICAL NAME :: Xanthen-9-one, 6-methoxy-1,2,8-trihydroxy-

CAS REGISTRY NUMBER :: 20882-75-1

BEILSTEIN REFERENCE NO. :: 1351024

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H10-O6

MOLECULAR WEIGHT :: 274.24

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 100 ug/plate

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 32,2290,1984

Safety Information

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

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