2,3,4-TRIFLUOROCINNAMICACID
Names
[ CAS No. ]:
207915-99-9
[ Name ]:
2,3,4-TRIFLUOROCINNAMICACID
[Synonym ]:
MFCD01862891
Chloro(dimethylamino)-N,N-dimethylmethaniminium hexafluorophosphate
Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
TCFH
N-[Chloro(dimethylamino)methylene]-N-methylmethanaminium hexafluorophosphate
Chloro-N,N,N’,N’-tetramethylformamidinium hexafluorophosphate
N,N,N′,N′-Tetramethylchloroformamidinium-hexafluorophosphate
N,N,N‘,N‘-Tetramethylchloroformamidinium-hexafluorophosphate
CHLORO-N,N,N',N'-TETRAMETHYLFORMAMIDINIUMHEXAFLUOROPHOSPHATE
TCFH,Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate
N,N,N',N'-Tetramethylchloroformamidinium-hexafluorophosphate
Chemical & Physical Properties
[ Melting Point ]:
99-104ºC
[ Molecular Formula ]:
C5H12ClF6N2P
[ Molecular Weight ]:
280.57900
[ Exact Mass ]:
280.03300
[ PSA ]:
19.84000
[ LogP ]:
3.79730
[ Storage condition ]:
2~8°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3.0
Articles
Chemistry 15 , 9404-9416, (2009)
We describe a new family of uronium-type coupling reagents that differ in their iminium moieties and leaving groups. The presence of the morpholino group in conjunction with an oxime derivative--espec...
N,N,N',N'-tetramethylchloroformamidinium hexafluorophosphate (TCFH), a powerful coupling reagent for bioconjugation.Bioconjug. Chem. 19 , 1968-1971, (2008)
Prodrugs are increasingly used as delivery vehicles for pharmaceutical agents that present solubility and/or pharmacokinetic/metabolic issues. In the course of the development of prodrugs for the anti...
L.A. Carpino, A. El-FahamJ. Am. Chem. Soc. 117 , 5401, (1995)