Boc-NH-PEG7-NH2

Names

[ CAS No. ]:
206265-98-7

[ Name ]:
Boc-NH-PEG7-NH2

[Synonym ]:
Boc-NH-PEG7-CH2CH2NH2
25-Amino-5,8,11,14,17,20,23-heptaoxa-2-azapentacosanoic Acid1,1-Dimethylethyl Ester

Biological Activity

[Description]:

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Density]:
1.075g/cm3

[ Boiling Point ]:
547.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₄₄N₂O₉

[ Molecular Weight ]:
468.58200

[ Flash Point ]:
285ºC

[ Exact Mass ]:
468.30500

[ PSA ]:
128.96000

[ LogP ]:
1.67720

[ Vapour Pressure ]:
4.75E-12mmHg at 25°C

[ Index of Refraction ]:
1.464

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Precursor & DownStream

Precursor

DownStream

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.