PDE2 inhibitor 4
Names
[ CAS No. ]:
2055160-19-3
[ Name ]:
PDE2 inhibitor 4
Biological Activity
[Description]:
PDE2 inhibitor 4 is a potent, selective, orally available inhibitor of PDE2 with IC50 of 2 nM, displays high selectivity versus other PDE isoforms; exhibits excellent pharmacokinetic properties in multiple species and improves cognitive performance in both the rat Novel Object Recognition and rhesus Object Recognition assays.
[References]
References 1. Stachel SJ, et al. ACS Med Chem Lett. 2018 Jul 26;9(8):815-820. View Related Products by Target Phosphodiesterase (PDE)
Chemical & Physical Properties
[ Molecular Formula ]:
C16H15F3N4O2
[ Molecular Weight ]:
352.317
Related Compounds
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