Mal-PEG8-NHS ester

Names

[ CAS No. ]:
2055033-05-9

[ Name ]:
Mal-PEG8-NHS ester

[Synonym ]:
MFCD26127784

Biological Activity

[Description]:

Mal-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₄₂N₂O₁₄

[ Molecular Weight ]:
618.63

Related Compounds

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