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PDD 00031705

Names

[ CAS No. ]:
2032096-45-8

[ Name ]:
PDD 00031705

Biological Activity

[Description]:

PDD00031705 is a benzimidazolone core cell-inactive inhibitor of Poly (ADP-ribose) glycohydrolase (PARG)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[In Vitro]

PDD00031705 shows some modest toxicity in in HeLa cells[1].

[References]

[1]. James DI, et al. First-in-Class Chemical Probes against Poly(ADP-ribose) Glycohydrolase (PARG) Inhibit DNA Repair with Differential Pharmacology to AZD2281. ACS Chem Biol. 2016 Nov 18;11(11):3179-3190. Epub 2016 Oct 12.

Chemical & Physical Properties

[ Molecular Formula ]:
C20H22N6O3S3

[ Molecular Weight ]:
490.62


Related Compounds

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