HKOCl-4m

Names

[ CAS No. ]:
2031170-88-2

[ Name ]:
HKOCl-4m

Biological Activity

[Description]:

HKOCl-4m is a selective and mitochondria-targeting rhodol-based fluorescent probe for monitoring mitochondrial hypochlorous acid (HOCl)[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[In Vitro]

HKOCl-4m (5 µM; 30 min) exhibits robust increase in fluorescence intensity upon addition of HOCl. HKOCl-4m has been successfully applied in detecting endogenous HOCl in RAW264.7 mouse macrophages. HKOCl-4m could be applied for monitoring the mitochondrial HOCl formation in living cells[1].

[References]

[1]. Xiaoyu Bai, et al. HKOCl-4: a rhodol-based yellow fluorescent probe for the detection of hypochlorous acid in living cells and tissues. Org. Chem. Front, 2020.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₃H₆₁BrCl₂N₃O₇P

[ Molecular Weight ]:
1153.96

Related Compounds

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