(5ξ)-Olean-13(18)-en-3-one

Names

[ CAS No. ]:
20248-08-2

[ Name ]:
(5ξ)-Olean-13(18)-en-3-one

[Synonym ]:
Olean-13(18)-en-3-one, (5ξ)-
(5ξ)-Olean-13(18)-en-3-one

Biological Activity

[Description]:

δ-Amyrenone (Delta-Amyrone) is a pentacyclic triterpene compound from S. lineare, with anti-inflammatory effects[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[In Vivo]

δ-Amyrone (4 mg/kg and 8 mg/kg; i.p.) inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice[1].

[References]

[1]. Niu X, et al.δ-Amyrone, a specific inhibitor of cyclooxygenase-2, exhibits anti-inflammatory effects in vitro and in vivo of mice. Int Immunopharmacol. 2014 Jul;21(1):112-8.

[2]. Niu X, et al.δ-Amyrone inhibits lipopolysaccharide-induced inflammatory cytokines and protects against endotoxic shock in mice. Chem Biol Interact. 2015 Oct 5;240:354-61.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
488.8±44.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₀H₄₈O

[ Molecular Weight ]:
424.702

[ Flash Point ]:
203.1±23.4 °C

[ Exact Mass ]:
424.370514

[ PSA ]:
17.07000

[ LogP ]:
10.51

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.534

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2914190090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2914190090

[ Summary ]:
2914190090 other acyclic ketones without other oxygen function。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Related Compounds

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