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Boc-Ala-Ala-Asp-pNA

Names

[ CAS No. ]:
201732-83-4

[ Name ]:
Boc-Ala-Ala-Asp-pNA

[Synonym ]:
L-α-Asparagine, N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-L-alanyl-N-(4-nitrophenyl)-
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-alanyl-L-alanyl-N-(4-nitrophenyl)-L-α-asparagine

Biological Activity

[Description]:

Boc-Ala-Ala-Asp-pNA is a chromogenic substrate of granzyme B. Boc-Ala-Ala-Asp-pNA can be used to test functional activity of granzyme B[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Apoptosis >> Caspase

[References]

[1]. Wagner C, et, al. Granzyme B and perforin: constitutive expression in human polymorphonuclear neutrophils. Blood. 2004 Feb 1;103(3):1099-104.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
859.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C21H29N5O9

[ Molecular Weight ]:
495.48

[ Flash Point ]:
473.7±34.3 °C

[ Exact Mass ]:
495.196533

[ LogP ]:
2.85

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.572

Related Compounds