Nangibotide

Names

[ CAS No. ]:
2014384-91-7

[ Name ]:
Nangibotide

Biological Activity

[Description]:

Nangibotide is a TREM-1 receptor inhibitor that can modulate innate immune response. Nangibotide can reduce systemic and in situ inflammatory reaction in rodent models of myocardial ischaemia‐reperfusion[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

TREM-1 receptor<[1]

[References]

[1]. Cuvier V, et, al. A first-in-man safety and pharmacokinetics study of nangibotide, a new modulator of innate immune response through TREM-1 receptor inhibition. Br J Clin Pharmacol. 2018 Oct;84(10):2270-2279.

Chemical & Physical Properties

[ Molecular Formula ]:
C₅₄H₈₂N₁₄O₂₂S₂

[ Molecular Weight ]:
1343.44

Related Compounds

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