VH032-NH-CO-CH2-NHBoc

Names

[ CAS No. ]:
2010986-19-1

[ Name ]:
VH032-NH-CO-CH2-NHBoc

Biological Activity

[Description]:

VH032-NH-CO-CH2-NHBoc is a Boc-modified VH032 (HY-120217) that acts as a ligand for VHL to recruit von Hippel-Lindau (VHL) proteins. VH032-NH-CO-CH2-NHBoc will remove the Boc protection under acidic conditions, and connect with the target protein ligand through a linker to form a PROTAC molecule, which is a key intermediate for the synthesis of PROTAC based on VHL ligand.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> Ligand for E3 Ligase

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₄₁N₅O₆S

[ Molecular Weight ]:
587.73

Related Compounds

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