Fmoc-Asp-NH2

Names

[ CAS No. ]:
200335-40-6

[ Name ]:
Fmoc-Asp-NH2

[Synonym ]:
Fmoc-L-isoasparagine
(S)-3-(((9H-fluoren-9-yl)methoxy)carbonylamino)-4-amino-4-oxobutanoic acid
Fmoc-Asp-NH2
Fmoc-IsoAsn-OH

Biological Activity

[Description]:

Fmoc-Asp-NH2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable

[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Chemical & Physical Properties

[ Density]:
1.362g/cm3

[ Boiling Point ]:
662.1ºC at 760 mmHg

[ Molecular Formula ]:
C₁₉H₁₈N₂O₅

[ Molecular Weight ]:
354.35700

[ Flash Point ]:
354.2ºC

[ Exact Mass ]:
354.12200

[ PSA ]:
118.72000

[ LogP ]:
2.94490

[ Vapour Pressure ]:
1.97E-18mmHg at 25°C

[ Index of Refraction ]:
1.626

[ Storage condition ]:
2-8°C

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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