Fmoc-DON-Boc

Names

[ CAS No. ]:
1998724-98-3

[ Name ]:
Fmoc-DON-Boc

Biological Activity

[Description]:

Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Rais R, et al. Discovery of 6-Diazo-5-oxo-l-norleucine (DON) Prodrugs with Enhanced CSF Delivery in Monkeys: A Potential Treatment for Glioblastoma. J Med Chem. 2016 Sep 22;59(18):8621-33.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₂₅N₃O₅

[ Molecular Weight ]:
435.47

Related Compounds

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