6-Oxo-1,6-dihydropyridine-2-carboxylic acid

Names

[ CAS No. ]:
19621-92-2

[ Name ]:
6-Oxo-1,6-dihydropyridine-2-carboxylic acid

[Synonym ]:
1,6-Dihydro-6-oxo-nicotinic acid
6-hydroxypyridine-3-carboxylic acid
2-Pyridinecarboxylicacid,1,6-dihydro-6-oxo
6-Hydroxynicotinic acid
2-Hydroxypyridine-6-carboxylic acid
2-hydroxy-6-picolinic acid
6-Hydroxyniacin
T6MVJ EVQ
1,6-dihydro-6-oxopyridine-3-carboxylic acid
3-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-
6-carboxy-2-hydroxy-pyridine
6-Hydroxypicolinic acid
6-Hydroxypyridine-2-carboxylic acid
6-hydroxopicolinic acid
6-Oxo-1,6-dihydro-3-pyridinecarboxylic acid
1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid
2-Pyridinecarboxylic acid, 6-hydroxy-
6-oxo-1,6-dihydropyridine-2-carboxylic acid
T6NJ BQ EVQ
EINECS 225-682-9
MFCD00192220
6-Hydroxy-2-pyridinecarboxylic Acid
EINECS 417-690-8
6-Oxo-1,6-dihydro-2-pyridinecarboxylic acid

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
493.0±30.0 °C at 760 mmHg

[ Melting Point ]:
270 °C (dec.)(lit.)

[ Molecular Formula ]:
C₆H₅NO₃

[ Molecular Weight ]:
139.109

[ Flash Point ]:
251.9±24.6 °C

[ Exact Mass ]:
139.026947

[ PSA ]:
70.42000

[ LogP ]:
-1.13

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.626

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

J. Med. Chem. 54 , 591-602, (2011)

Fragment-based lead design (FBLD) has been used to identify new metal-binding groups for metalloenzyme inhibitors. When screened at 1 mM, a chelator fragment library (CFL-1.1) of 96 compounds produced...

Synthesis, molecular, spectroscopic and catalytic characterization of ruthenium (II) complexes with pyridine-2-carboxylic acid derivatives ligands. Malecki JG, et al.

Polyhedron 48(1) , 21-30, (2012)

Computational study of the intramolecular proton transfer between 6-hydroxypicolinic acid tautomeric forms and intermolecular hydrogen bonding in their dimers. Kazemi Riabi SH, et al.

Phys. Chem. Res. 1 , 117-125, (2013)