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Histamine trifluromethyl toluidine

Names

[ CAS No. ]:
195867-54-0

[ Name ]:
Histamine trifluromethyl toluidine

[Synonym ]:
htmt dimaleate
htmt

Biological Activity

[Description]:

HTMT (dimaleate) is a potent histamine H1 and H2 receptor agonist. HTMT (dimaleate) is 4 x 104 times more active than histamine in H2-mediated effects in natural suppressor cells[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor
Research Areas >> Inflammation/Immunology
Signaling Pathways >> GPCR/G Protein >> Histamine Receptor

[Target]

H1 Receptor

H2 Receptor


[References]

[1]. Khan MM, Marr-Leisy D, Verlander MS, Bristow MR, Strober S, Goodman M, Melmon KL. The effects of derivatives of histamine on natural suppressor cells. J Immunol. 1986 Jul 1;137(1):308-14.

Chemical & Physical Properties

[ Boiling Point ]:
922.2ºC at 760mmHg

[ Molecular Formula ]:
C27H33F3N4O9

[ Molecular Weight ]:
614.56800

[ Flash Point ]:
511.5ºC

[ Exact Mass ]:
614.22000

[ PSA ]:
219.01000

[ LogP ]:
4.03570

[ Vapour Pressure ]:
0mmHg at 25°C

[ Storage condition ]:
2-8°C

Safety Information

[ Safety Phrases ]:
S22;S24/25

Related Compounds