MP-Ala-Ala-PAB

Names

[ CAS No. ]:
1949793-47-8

[ Name ]:
MP-Ala-Ala-PAB

Biological Activity

[Description]:

MP-Ala-Ala-PAB is a cleavable ADC Linker (ADC Linker). Fmoc-Ala-Ala-PAB can be used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADC 由一种抗体和 ADC 毒素分子通过 ADC 连接子组合而成[1]。

[References]

[1]. Wayne C Widdison, et al. Development of Anilino-Maytansinoid ADCs that Efficiently Release Cytotoxic Metabolites in Cancer Cells and Induce High Levels of Bystander Killing. Bioconjug Chem. 2015 Nov 18;26(11):2261-78.  

Chemical & Physical Properties

[ Molecular Formula ]:
C20H24N4O6

[ Molecular Weight ]:
416.43

Related Compounds