3-Pyridineacrylic acid

Names

[ CAS No. ]:
19337-97-4

[ Name ]:
3-Pyridineacrylic acid

[Synonym ]:
3-Pyridineacrylic acid
trans-3-(3-Pyridyl)acrylic acid
2-Propenoic acid, 3-(3-pyridinyl)-, (2E)-
(2E)-3-(3-Pyridinyl)acrylic acid
(2E)-3-(Pyridin-3-yl)acrylic acid
Pyridine-3-acrylic acid
MFCD00006410
(2E)-3-(pyridin-3-yl)prop-2-enoic acid
3-PYRIDYLACRYLIC ACID
3-PYRIDINYL-ACRYLIC ACID
3-PYRIDIN-3-YL-ACRYLIC ACID
RARECHEM BK HC S246
EINECS 214-424-0

Biological Activity

[Description]:

trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid. trans-3-(3-Pyridyl)acrylic acid shows antiviral activity against tobacco mosaic virus (TMV)[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Wu M, et al. Discovery and SARs of trans-3-aryl acrylic acids and their analogs as novel anti-tobacco mosaic virus (TMV) agents. PLoS One. 2013;8(2):e56475.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
307.6±17.0 °C at 760 mmHg

[ Melting Point ]:
232-235ºC

[ Molecular Formula ]:
C₈H₇NO₂

[ Molecular Weight ]:
149.15

[ Flash Point ]:
139.8±20.9 °C

[ Exact Mass ]:
149.047684

[ PSA ]:
50.19000

[ LogP ]:
1.17

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.625

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Structure-activity relationships of trans-substituted-propenoic acid derivatives on the nicotinic acid receptor HCA2 (GPR109A).

Bioorg. Med. Chem. Lett. 21 , 2736-9, (2011)

Nicotinic acid (niacin) has been used for decades as an antidyslipidemic drug in man. Its main target is the hydroxy-carboxylic acid receptor HCA2 (GPR109A), a G protein-coupled receptor. Other acids ...

Related Compounds

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