Zabedosertib

Names

[ CAS No. ]:
1931994-81-8

[ Name ]:
Zabedosertib

Biological Activity

[Description]:

Zabedosertib (BAY 1834845) is a IRAK4 inhibitor with immunomodulatory potential. IRAK4 is a protein kinase involved in signaling innate immune responses from Toll-like receptors[1].

[Related Catalog]:

Signaling Pathways >> Immunology/Inflammation >> IRAK

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IRAK

[References]

[1]. Bothe, Ulrich; Siebenreicher, Holger; Schmidt, Nicole; Nubbemeyer, Reinhard; Boemer, Ulf; Guenther, Judith; Steuber, Holger; Lange, Martin; Stegmann, Christian; Sutter, Andreas; et al.New substituted indazoles, methods for the production thereof, pharmaceutical preparations that contain said new substituted indazoles, and use of said new substituted indazoles to produce drugs.WO2016083433A1

Chemical & Physical Properties

[ Boiling Point ]:
620.7±55.0 °C(Predicted)

[ Molecular Formula ]:
C₂₀H₂₁F₃N₄O₄S

[ Molecular Weight ]:
470.47

[ Storage condition ]:
2-8°C

Related Compounds

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