Acetamide,N-(4-ethoxyphenyl)-N-hydroxy-
Names
[ CAS No. ]:
19315-64-1
[ Name ]:
Acetamide,N-(4-ethoxyphenyl)-N-hydroxy-
[Synonym ]:
N-Hydroxy-p-acetophenetidide
4'-Ethoxy-N-hydroxyacetanilid
p-Acetophenetidide,N-hydroxy
N-hydroxyphenacetin
N-Hydroxy-p-ethoxyacetanilid
Chemical & Physical Properties
[ Density]:
1.2g/cm3
[ Boiling Point ]:
345.5ºC at 760mmHg
[ Molecular Formula ]:
C10H13NO3
[ Molecular Weight ]:
195.21500
[ Flash Point ]:
162.7ºC
[ Exact Mass ]:
195.09000
[ PSA ]:
49.77000
[ LogP ]:
1.82740
[ Vapour Pressure ]:
2.33E-05mmHg at 25°C
[ Index of Refraction ]:
1.571
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AK8380000
- CHEMICAL NAME :
- Acetohydroxamic acid, N-(4-ethoxyphenyl)-
- CAS REGISTRY NUMBER :
- 19315-64-1
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 8
- MOLECULAR FORMULA :
- C10-H13-N-O3
- MOLECULAR WEIGHT :
- 195.24
- WISWESSER LINE NOTATION :
- QMV1R DO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 702 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 15 gm/kg/73W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors Kidney, Ureter, Bladder - Kidney tumors
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Embryo
- DOSE/DURATION :
- 100 ug/L
- REFERENCE :
- NCIMAV National Cancer Institute, Monograph. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) No.1- 1959- Volume(issue)/page/year: 58,21,1981 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 13,141,1977 IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 24,135,1980
Safety Information
[ HS Code ]:
2924299090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2924299090
[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%