JAK3i
Names
[ CAS No. ]:
1918238-72-8
[ Name ]:
JAK3i
Biological Activity
[Description]:
JAK3i is a selective, covalent JAK3 kinase inhibitor with IC50 of 0.43 nM, shows high selectivity (>3,000-fold) against the closely related kinase domains in JAK1, JAK2, or TYK2, displays 1,300-fold, 600-fold, and 50-fold over EGFR, ITK, and BTK respectively.
[References]
References 1. Smith GA, et al. Nat Chem Biol. 2016 May;12(5):373-9. View Related Products by Target JAK
Chemical & Physical Properties
[ Molecular Formula ]:
C18H15FN4O3
[ Molecular Weight ]:
354.34
Related Compounds
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