H-Glu-Glu-Lys-Leu-Ile-Val-Val-Ala-Phe-OH

Names

[ Name ]:
H-Glu-Glu-Lys-Leu-Ile-Val-Val-Ala-Phe-OH

[Synonym ]:
(2S,5S,8S,11S,14S,17S,20S,23S)-23-Amino-17-(4-aminobutyl)-11-[(2S)-2-butanyl]-20-(2-carboxyethyl)-1-{[(1S)-1-carboxy-2-phenylethyl]imino}-1,4,7,10,13,16,19,22-octahydroxy-14-isobutyl-5,8-diisopropyl-2-methyl-3,6,9,12,15,18,21-heptaazahexacosa-3,6,9,12,15,18,21-heptaen-26-oic acid
Benzenepropanoic acid, α-[[(2S,5S,8S,11S,14S,17S,20S,23S)-23-amino-17-(4-aminobutyl)-25-carboxy-20-(2-carboxyethyl)-1,4,7,10,13,16,19,22-octahydroxy-2-methyl-5,8-bis(1-methylethyl)-11-[(1S)-1-meth ylpropyl]-14-(2-methylpropyl)-3,6,9,12,15,18,21-heptaazapentacosa-3,6,9,12,15,18,21-heptaen-1-ylidene]amino]-, (αS)-

Biological Activity

[Description]:

EEKLIVVAF is a pepitide, can be recognized on HLA-B44 by the anti-melanoma cytolytic T-cell (CTL) clone LB33- CTL-159/5[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

EEKLIVVAF can be recognized by CTL clone on C1RB*4402 and C1R-B*4403 cells, and (45 ng/mL and 160 ng/mL, respectively; 30 min; 20 ℃) shows the ability to compete with a standard peptide for binding to HLA-B*4402 and HLA-B*4403 molecules[1].

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1148.7±75.0 °C at 760 mmHg

[ Molecular Formula ]:
C₅₀H₈₂N₁₀O₁₄

[ Molecular Weight ]:
1047.245

[ Flash Point ]:
648.5±37.1 °C

[ Exact Mass ]:
1046.601196

[ LogP ]:
9.32

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.596

Related Compounds

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