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CC-99677

Names

[ CAS No. ]:
1887069-10-4

[ Name ]:
CC-99677

Biological Activity

[Description]:

CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). CC-99677 is extracted from patent WO2020236636, compound 1[1].

[Related Catalog]:

Signaling Pathways >> MAPK/ERK Pathway >> MAPKAPK2 (MK2)
Research Areas >> Inflammation/Immunology

[Target]

MK2[1]


[In Vitro]

CC-99677 is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM)[1].

[References]

[1]. WO2020236636

Chemical & Physical Properties

[ Molecular Formula ]:
C22H20ClN5O3S

[ Molecular Weight ]:
469.94

Related Compounds

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