Olutasidenib

Names

[ Name ]:
Olutasidenib

Biological Activity

[Description]:

Olutasidenib is a highly potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 that could be used in the treatment of acute myeloid leukemia.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Isocitrate Dehydrogenase (IDH)

Research Areas >> Inflammation/Immunology

[Target]

IDH1[1].

[References]

[1]. JM Watts, et al. A phase 1 dose escalation study of the IDH1m inhibitor, FT-2102, in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

[Related Small Molecules]

AG-120 | Enasidenib | AGI-5198 | Vorasidenib (AG-881) | AGI-6780 | GSK864 | IDH-305 | BAY-1436032 | Mutant IDH1 inhibitor | Mutant IDH1-IN-1 | Mutant IDH1-IN-2

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₅ClN₄O₂

[ Molecular Weight ]:
354.79