Gepefrine

Names

[ Name ]:
Gepefrine

[Synonym ]:
unii-v51rrx51vh

Biological Activity

[Description]:

Gepefrine is an orally active pressor agent and sympathomimetic agent. Gepefrine improves the early orthostatic disregulation of the arterial pressure[1][2][3].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Peters FT, et al. Drug testing in blood: validated negative-ion chemical ionization gas chromatographic-mass spectrometric assay for determination of amphetamine and methamphetamine enantiomers and its application to toxicology cases. Clin Chem. 2002 Sep;48(9):1472-85.

[2]. Lossnitzer K, et al. Vergleichende Untersuchungen antihypotensiv wirksamer Sympathikomimetika im Kipptisch-Versuch [Therapy of orthostatic dysregulation. Comparative studies on anti-hypotensive sympathomimetics with a tilt-table test]. Fortschr Med. 1980 Aug 7;98(29):(1133-6). German.

[3]. Bachour G, et al. [Therapy of orthostatic dysregulation with gepefrin. Study with continuous telemetric blood pressure monitoring]. Z Kardiol. 1985 Apr;74(4):228-33. German.

Chemical & Physical Properties

[ Density]:
1.07g/cm3

[ Boiling Point ]:
281ºC at 760mmHg

[ Molecular Formula ]:
C₉H₁₃NO

[ Molecular Weight ]:
151.20600

[ Flash Point ]:
123.7ºC

[ Exact Mass ]:
151.10000

[ PSA ]:
46.25000

[ LogP ]:
1.98220

[ Vapour Pressure ]:
0.00215mmHg at 25°C

[ Index of Refraction ]:
1.562

Related Compounds

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