Estra-1,3,5(10)-triene-3,17-diol,4-fluoro-, (17b)-(9CI)
Names
[ CAS No. ]:
1881-37-4
[ Name ]:
Estra-1,3,5(10)-triene-3,17-diol,4-fluoro-, (17b)-(9CI)
[Synonym ]:
N-triisopropylsilyl-4-fluoro-7-azaindole
4-Fluoroestradiol
1-triisopropyl-4-fluoro-7-azaindole
Chemical & Physical Properties
[ Density]:
1.225g/cm3
[ Boiling Point ]:
427.1ºC at 760mmHg
[ Molecular Formula ]:
C18H23FO2
[ Molecular Weight ]:
290.37200
[ Flash Point ]:
212.1ºC
[ Exact Mass ]:
290.16800
[ PSA ]:
40.46000
[ LogP ]:
3.74830
[ Vapour Pressure ]:
4.7E-08mmHg at 25°C
[ Index of Refraction ]:
1.586
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG7535000
- CHEMICAL NAME :
- Estra-1,3,5(10)-triene-3,17-beta-diol, 4-fluoro-
- CAS REGISTRY NUMBER :
- 1881-37-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H23-F-O2
- MOLECULAR WEIGHT :
- 290.41
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 360 mg/kg/15W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
- REFERENCE :
- MOPMA3 Molecular Pharmacology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1965- Volume(issue)/page/year: 23,278,1983