[Arg15,20,21, Leu17] VIP-Gly-Lys-Arg-NH2

Names

[ CAS No. ]:
186844-13-3

[ Name ]:
[Arg15,20,21, Leu17] VIP-Gly-Lys-Arg-NH2

Biological Activity

[Description]:

[Arg15,20,21, Leu17] VIP-Gly-Lys-Arg-NH2 is a vasoactive intestinal polypeptide (VIP) analog with relaxant effects[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[In Vitro]

[Arg15,20,21, Leu17] VIP-Gly-Lys-Arg-NH2 的 N 端和 C 端氨基酸序列都发生了改变，使其在性质上更加碱性[1]。 [Arg15,20,21, Leu17] VIP-Gly-Lys-Arg-NH2（0.1、0.3 或 1 μM；0-6 小时）在豚鼠气管中产生显着的浓度依赖性气管平滑肌松弛作用 [1]。

[References]

[1]. S Yoshihara, et al. A novel long-acting VIP analog in the guinea pig trachea in vitro. Peptides. 1998;19(3):593-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C162H267N57O45

[ Molecular Weight ]:
3733.20

Related Compounds