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Raloxifene 4-Monomethyl Ether

Names

[ CAS No. ]:
185415-07-0

[ Name ]:
Raloxifene 4-Monomethyl Ether

Biological Activity

[Description]:

Raloxifene 4-Monomethyl Ether (Compound 37) is a Raloxifene derivative that inhibits estrogen receptor α. Raloxifene 4-Monomethyl Ether inhibits MCF-7 cells with an IC50 of 1 μM and a pIC50 of 6[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR

[References]

[1]. Chang YH, et al. Computational study of estrogen receptor-alpha antagonist with three-dimensional quantitative structure-activity relationship, support vector regression, and linear regression methods. Int J Med Chem. 2013;2013:743139.

Chemical & Physical Properties

[ Molecular Formula ]:
C29H29NO4S

[ Molecular Weight ]:
487.61

Related Compounds