(-)-cubebin

Names

[ Name ]:
(-)-cubebin

[Synonym ]:
CUBEBIN
tetrahydro-3,4-dipiperonylfuran-2-ol
Cubebine
2-Furanol,tetrahydro-3,4-dipiperonyl

Biological Activity

[Description]:

Cubebin is a dibenzylbutyrolactone lignan isolated from the crude hexane extract of the leaves of Zanthoxyllum naranjillo. Cubebin shows a significant anti-inflammatory activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Bastos JK, et al. Anti-inflammatory activity of cubebin, a lignan from the leaves of Zanthoxyllum naranjillo Griseb. J Ethnopharmacol. 2001;75(2-3):279-282.

Chemical & Physical Properties

[ Density]:
1.393g/cm3

[ Boiling Point ]:
526.8ºC at 760mmHg

[ Melting Point ]:
131-132ºC

[ Molecular Formula ]:
C₂₀H₂₀O₆

[ Molecular Weight ]:
356.36900

[ Flash Point ]:
272.4ºC

[ Exact Mass ]:
356.12600

[ PSA ]:
66.38000

[ LogP ]:
2.51020

[ Vapour Pressure ]:
6.29E-12mmHg at 25°C

[ Index of Refraction ]:
1.641

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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