BTK-IN-27

Names

[ Name ]:
BTK-IN-27

Biological Activity

[Description]:

BTK-IN-27 (example 8) is a BTK inhibitor (IC50: 0.2 nM). BTK-IN-27 shows anti-proliferative activity in TMD8 cells (IC50: < 5 nM). BTK-IN-27 can be used for research of cancer, lymphoma, leukemia and immunological diseases[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

[Target]

0.2 nM (BTK)[1]

[References]

[1]. Mathew CALDER, et al. Pyrazolopyrimidine derivatives useful as inhibitors of bruton's tyrosine kinase. Patent. WO2015189620.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₃₅N₇O₂

[ Molecular Weight ]:
537.66

Related Compounds

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