SH-BC-893
Names
[ CAS No. ]:
1841409-92-4
[ Name ]:
SH-BC-893
Biological Activity
[Description]:
SH-BC-893 is a water-soluble, orally bioavailable synthetic sphingolipid that triggers nutrient transporter internalization and also blocks lysosome-dependent nutrient generation pathways in cancer cells, activates protein phosphatase 2A (PP2A), leading to mislocalization of the lipid kinase PIKfyve; selectively kills cells expressing an activated form of the anabolic oncogene Ras in vitro and in vivo.
[References]
References 1. Kim SM, et al. J Clin Invest. 2016 Nov 1;126(11):4088-4102. View Related Products by Target Other Targets
Chemical & Physical Properties
[ Molecular Formula ]:
C19H32ClNO
[ Molecular Weight ]:
325.921