Pomalidomide-PEG6-butyl iodide
Names
[ CAS No. ]:
1835705-74-2
[ Name ]:
Pomalidomide-PEG6-butyl iodide
Biological Activity
[Description]:
Pomalidomide-PEG6-butyl iodide is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 6-unit PEG linker used in PROTAC technology[1].
[Related Catalog]:
[Target]
Cereblon
[In Vitro]
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C31H44IN3O11
[ Molecular Weight ]:
761.60