1,14-Diazido-3,6,9,12-tetraoxatetradecane

Names

[ CAS No. ]:
182760-73-2

[ Name ]:
1,14-Diazido-3,6,9,12-tetraoxatetradecane

[Synonym ]:
1,14-diazido-3,6,9,12-tetraoxatetradecane

Biological Activity

[Description]:

Azido-PEG4-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₀H₂₀N₆O₄

[ Molecular Weight ]:
288.30400

[ Exact Mass ]:
288.15500

[ PSA ]:
136.42000

[ LogP ]:
0.57892

Safety Information

[ Hazard Codes ]:
Xi

Precursor & DownStream

Precursor

DownStream

Related Compounds

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