Desmethylanethol trithione

Names

[ Name ]:
Desmethylanethol trithione

[Synonym ]:
Desmethylanethol trithione
Desmethylanethol dithiolthione
desmethyl anethole trithione
4-Hydroxyanethole trithione
Desmethyl-adt
5-(4-Hydroxyphenyl)-3H-1,2-dithiole-3-thione

Biological Activity

[Description]:

ADT-OH is a hydrogen sulfide-releasing donor. ADT-OH induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. ADT-OH has the potential for the research of cancer diseases[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Cai F, et al. ADT-OH, a hydrogen sulfide-releasing donor, induces apoptosis and inhibits the development of melanoma in vivo by upregulating FADD. Cell Death Dis. 2020;11(1):33.

Chemical & Physical Properties

[ Density]:
1.48g/cm3

[ Boiling Point ]:
322.2ºC at 760mmHg

[ Melting Point ]:
191-192 ºC

[ Molecular Formula ]:
C₉H₆OS₃

[ Molecular Weight ]:
226.33800

[ Flash Point ]:
148.6ºC

[ Exact Mass ]:
225.95800

[ PSA ]:
106.47000

[ LogP ]:
3.10180

[ Vapour Pressure ]:
0.000284mmHg at 25°C

[ Index of Refraction ]:
1.757

[ Storage condition ]:
2-8°C

Safety Information

[ Hazard Codes ]:
Xi

[ HS Code ]:
2930909090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2930909090

[ Summary ]:
2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%